Across TCGA patient cohorts, FANCF mutation is significantly associated with the RNA expression of many other genes, with 65 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FANCF-associated genes across cancer lineages are RNA5SP402, TUBAP4, and RNA5SP408. Each is linked with FANCF in more than 1 cancer types. Because this analysis shows association rather than direction, both FANCF-to-partner and partner-to-FANCF results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCF→partner) and Y-score (partner→FANCF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP402 →	+0.505	+5.411	<.001	.005	3	2
UCEC	TUBAP4 →	+0.221	+2.970	<.001	.003	3	2
LUAD	RNA5SP408 →	+0.308	+7.930	<.001	.008	3	2
BLCA	IGHVII-46-1 →	+1.292	+5.177	<.001	.007	3	1
BLCA	OR11H2 →	+0.056	+5.588	<.001	.004	3	1
BLCA	PABPC1P5 →	+0.043	+5.329	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

Exploration

FANCF survival (RNA) · tumor vs normal (RNA) · all FANCF data types