Across TCGA patient cohorts, FANCF mutation is significantly associated with the immune_cell of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FANCF-associated genes across cancer lineages are Adipocytes, CD8+ Tcm, and cDC. Each is linked with FANCF in more than 2 cancer types. Because this analysis shows association rather than direction, both FANCF-to-partner and partner-to-FANCF results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCF→partner) and Y-score (partner→FANCF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adipocytes →	+0.022	+2.507	.036	.022	3	3
HNSC	CD8+ Tcm →	+0.063	+3.813	.003	.042	3	1
UCEC	cDC →	+0.234	+3.008	<.001	.019	3	1
UCEC	DC →	+0.034	+3.444	.004	.009	3	1
UCEC	Erythrocytes →	+0.051	+2.879	<.001	.033	3	1
UCEC	Hepatocytes →	+0.012	+3.021	.042	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

FANCF survival (RNA) · tumor vs normal (RNA) · all FANCF data types