Across TCGA cell cohorts, FANCF RNA expression is significantly associated with the go_rna of many other GO terms, with 4,203 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FANCF-associated GO terms across cancer lineages are Negative regulation of dendritic cell antigen processing and presentation, Regulation of syncytium formation by plasma membrane fusion, and Chaperone-mediated autophagy. Each is linked with FANCF in more than 7 cancer types. Because this analysis shows association rather than direction, both FANCF-to-partner and partner-to-FANCF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCF→partner) and Y-score (partner→FANCF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of dendritic cell antigen processing and presentation →	-1.303	-0.686	.001	.001	3	8
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.112	+1.057	<.001	<.001	3	8
BLOOD_Leukemia	Chaperone-mediated autophagy →	-0.073	-0.497	<.001	<.001	3	8
LARGE_INTESTINE	Inflammatory cell apoptotic process →	-0.225	-0.620	<.001	.001	3	8
BONE	DNA replication-dependent chromatin disassembly →	+0.133	+0.698	.002	.003	3	7
BLOOD_Lymphoma	Regulation of DNA damage checkpoint →	+0.070	+0.779	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,203 associations by consensus.

Exploration

FANCF survival (RNA) · tumor vs normal (RNA) · all FANCF data types