FANCD2

Across TCGA patient cohorts, FANCD2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,571 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FANCD2-associated genes across cancer lineages are CDKN3, CENPI, and OIP5. Each is linked with FANCD2 in more than 6 cancer types. Because this analysis shows association rather than direction, both FANCD2-to-partner and partner-to-FANCD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FANCD2 versus CDKN3 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCD2→partner) and Y-score (partner→FANCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CDKN3 →	+1.534	+0.545	<.001	<.001	3	7
COAD	CENPI →	+1.088	+0.997	<.001	.001	3	7
COAD	OIP5 →	+0.955	+0.679	<.001	<.001	3	7
UCEC	ASF1B →	+1.223	+0.476	<.001	<.001	3	7
COAD	RAD51AP1 →	+1.403	+1.295	<.001	<.001	3	7
COAD	CENPA →	+1.297	+1.092	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,571 associations by consensus.

FANCD2 vs CDKN3 — OV

Explore this scatter interactively →