FANCC

Across TCGA cell cohorts, FANCC RNA expression is significantly associated with the go_rna of many other GO terms, with 4,900 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FANCC-associated GO terms across cancer lineages are Regulation of chromosome condensation, Immunoglobulin heavy chain V-D-J recombination, and Regulation of cell cycle checkpoint. Each is linked with FANCC in more than 18 cancer types. Because this analysis shows association rather than direction, both FANCC-to-partner and partner-to-FANCC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome condensation grouped by FANCC-low versus FANCC-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCC→partner) and Y-score (partner→FANCC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of chromosome condensation →	+0.212	+1.045	<.001	<.001	3	19
SOFT_TISSUE	Immunoglobulin heavy chain V-D-J recombination →	+0.193	+0.987	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Regulation of cell cycle checkpoint →	+0.117	+1.234	<.001	<.001	3	17
SOFT_TISSUE	Positive regulation of cell cycle →	+0.079	+0.998	<.001	<.001	3	17
BONE	Chromosome condensation →	+0.187	+1.122	.005	<.001	3	17
SOFT_TISSUE	Regulation of sister chromatid cohesion →	+0.105	+0.899	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,900 associations by consensus.

Regulation of chromosome condensation by FANCC expression — BLOOD_Lymphoma

Explore this box plot interactively →