Across TCGA patient cohorts, FAN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,305 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAN1-associated proteins across cancer lineages are SRP9, RPUSD2, and RTF1. Each is linked with FAN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FAN1-to-partner and partner-to-FAN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAN1→partner) and Y-score (partner→FAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SRP9 →	+0.303	+0.382	.001	.009	3	7
LSCC	RPUSD2 →	+0.295	+0.461	<.001	<.001	3	6
LSCC	RTF1 →	+0.310	+0.578	<.001	<.001	3	6
LSCC	ANP32A →	+0.388	+0.612	<.001	<.001	3	6
BRCA	UBE3A →	+0.208	+0.497	.001	<.001	3	6
GBM	ACIN1 →	+0.235	+0.214	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,305 associations by consensus.

Exploration

FAN1 survival (RNA) · tumor vs normal (RNA) · all FAN1 data types