Across TCGA cell cohorts, FAN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,158 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FAN1-associated GO terms across cancer lineages are Microtubule nucleation, Positive regulation of cilium assembly, and Microtubule polymerization. Each is linked with FAN1 in more than 16 cancer types. Because this analysis shows association rather than direction, both FAN1-to-partner and partner-to-FAN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAN1→partner) and Y-score (partner→FAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Microtubule nucleation →	+0.130	+0.836	<.001	<.001	3	17
URINARY_TRACT	Positive regulation of cilium assembly →	+0.086	+0.839	.005	<.001	3	16
BONE	Microtubule polymerization →	+0.121	+0.855	<.001	<.001	3	16
SOFT_TISSUE	Spliceosomal complex assembly →	+0.101	+0.913	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	RNA catabolic process →	+0.065	+0.814	<.001	<.001	3	15
SOFT_TISSUE	DNA biosynthetic process →	+0.068	+0.926	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,158 associations by consensus.

Exploration

FAN1 survival (RNA) · tumor vs normal (RNA) · all FAN1 data types