Across TCGA patient cohorts, FAM9C mutation is significantly associated with the RNA expression of many other genes, with 345 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM9C-associated genes across cancer lineages are RNU4ATAC5P, SSU72, and CCDC134. Each is linked with FAM9C in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM9C-to-partner and partner-to-FAM9C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM9C→partner) and Y-score (partner→FAM9C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU4ATAC5P →	+0.279	+7.930	<.001	.008	3	3
UCEC	SSU72 →	+0.380	+3.218	.006	.009	3	2
UCEC	CCDC134 →	+0.606	+3.480	.004	.002	3	2
UCEC	WDR5 →	+0.526	+3.491	.008	.002	3	2
UCEC	MIRLET7BHG →	+0.688	+3.191	<.001	.009	3	2
UCEC	SPG7 →	+0.590	+3.364	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 345 associations by consensus.

Exploration

FAM9C survival (RNA) · tumor vs normal (RNA) · all FAM9C data types