Across TCGA patient cohorts, FAM9C mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM9C-associated genes across cancer lineages are EGFR_pY1068, Ku80, and Syk. Each is linked with FAM9C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM9C-to-partner and partner-to-FAM9C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM9C→partner) and Y-score (partner→FAM9C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.288	-3.321	.028	.010	3	1
UCEC	Ku80 →	+0.263	+2.183	.033	.035	3	1
UCEC	Syk →	+0.442	+3.335	.024	.005	3	1
UCEC	Caspase-7-cleavedD198 →	+0.858	+3.019	.005	.019	3	1
UCEC	INPP4B →	-0.409	-3.308	.015	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

FAM9C survival (RNA) · tumor vs normal (RNA) · all FAM9C data types