FAM9A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM9A mutation is significantly associated with the RNA expression of many other genes, with 1,508 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM9A-associated genes across cancer lineages are SIGLEC16, GTSE1, and H2AC12. Each is linked with FAM9A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM9A-to-partner and partner-to-FAM9A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM9A→partner) and Y-score (partner→FAM9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSIGLEC16 →+0.328+1.850.006<.00132
UCECGTSE1 →+0.472+1.871.006<.00132
UCECH2AC12 →+0.613+2.070<.001.00132
UCECNR2C2AP →+0.414+3.364<.001<.00132
UCECAP1B1P1 →+0.048+1.354.009.00832
UCECRASSF1-AS1 →+0.457+3.043<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,508 associations by consensus.

Exploration