FAM98B

Across TCGA pan-cancer cohorts, FAM98B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FAM98B data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FAM98B mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM98B expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

LUAD, LSCC, and CCRCC are the cancer types where FAM98B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	II,III,IV	0.676	0.881	.011	13	view →
LSCC	DFS	Median	III,IV	0.359	0.868	.006	9	view →
CCRCC	OS	Median	All	1.000	0.672	.011	8	view →
UCEC	DFS	Median	II,III,IV	0.503	0.872	.027	8	view →
HNSC	OS	Quartile	All	0.568	0.786	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FAM98B–LUAD (DFS)

Open the LUAD breakdown →