FAM98B

Across TCGA cell cohorts, FAM98B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,683 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM98B-associated GO terms across cancer lineages are Protein localization to kinetochore, Mitotic nuclear division, and Regulation of chromosome segregation. Each is linked with FAM98B in more than 19 cancer types. Because this analysis shows association rather than direction, both FAM98B-to-partner and partner-to-FAM98B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to kinetochore grouped by FAM98B-low versus FAM98B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM98B→partner) and Y-score (partner→FAM98B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.172	+0.958	<.001	<.001	3	20
OESOPHAGUS	Mitotic nuclear division →	+0.105	+0.728	.004	.008	3	18
URINARY_TRACT	Regulation of chromosome segregation →	+0.121	+0.872	.002	<.001	3	17
URINARY_TRACT	Protein localization to chromosome, centromeric region →	+0.176	+0.804	<.001	<.001	3	17
URINARY_TRACT	Negative regulation of mitotic metaphase/anaphase transition →	+0.204	+0.826	<.001	<.001	3	17
OESOPHAGUS	Kinetochore assembly →	+0.166	+0.837	.003	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,683 associations by consensus.

Protein localization to kinetochore by FAM98B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →