FAM98B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM98B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FAM98B-associated genes across cancer lineages are GAGE12H, SERPINA7, and OR7G1. Each is linked with FAM98B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM98B-to-partner and partner-to-FAM98B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE12H grouped by FAM98B-low versus FAM98B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM98B→partner) and Y-score (partner→FAM98B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEGAGE12H →+0.066+4.437<.001.00431
LUNG_NSCLC_LUADSERPINA7 →+0.013+5.228<.001.00531
LUNG_NSCLC_LUADOR7G1 →+0.023+6.266<.001<.00131
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GAGE12H by FAM98B expression — LARGE_INTESTINE

Box plot of GAGE12H in FAM98B-low vs FAM98B-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration