FAM98A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM98A mutation is significantly associated with the RNA expression of many other genes, with 2,544 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM98A-associated genes across cancer lineages are MSANTD2P1, MIR6803, and NFILZ. Each is linked with FAM98A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM98A-to-partner and partner-to-FAM98A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSANTD2P1 grouped by FAM98A-low versus FAM98A-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM98A→partner) and Y-score (partner→FAM98A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCMSANTD2P1 →+0.025+4.647<.001.00733
UCECMIR6803 →+0.086+3.954<.001.00633
CESCNFILZ →+0.062+4.384<.001.00833
READSDR16C6P →+0.080+5.653<.001.00332
CESCRNU6-249P →+0.303+3.653.001.00932
COADRNU6-742P →+0.708+3.636<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,544 associations by consensus.

MSANTD2P1 by FAM98A expression — LIHC

Box plot of MSANTD2P1 in FAM98A-low vs FAM98A-high samples in LIHC.

Explore this box plot interactively →

Exploration