FAM98A

Across TCGA patient cohorts, FAM98A mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM98A-associated genes across cancer lineages are MIG-6, ATM, and CDK1. Each is linked with FAM98A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM98A-to-partner and partner-to-FAM98A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIG-6 grouped by FAM98A-low versus FAM98A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM98A→partner) and Y-score (partner→FAM98A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIG-6 →	+0.087	+1.874	.019	.049	3	2
UCEC	ATM →	-0.376	-1.415	.027	.046	3	2
UCEC	CDK1 →	+0.122	+1.887	.031	.029	3	2
UCEC	eIF4E →	+0.169	+3.183	.032	.009	3	1
UCEC	ER-alpha →	-0.616	-3.308	.046	.009	3	1
UCEC	ERK2 →	+0.181	+1.415	.012	.046	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

MIG-6 by FAM98A expression — UCEC

Explore this box plot interactively →