FAM91A1

Across TCGA cell cohorts, FAM91A1 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM91A1-associated genes across cancer lineages are C9orf57, IFNG, and BTNL8. Each is linked with FAM91A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM91A1-to-partner and partner-to-FAM91A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C9orf57 grouped by FAM91A1-low versus FAM91A1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM91A1→partner) and Y-score (partner→FAM91A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C9orf57 →	+0.098	+3.187	<.001	.001	3	2
BLOOD_Leukemia	IFNG →	+0.152	+3.304	<.001	.001	3	1
BLOOD_Leukemia	BTNL8 →	+0.453	+3.506	<.001	.008	3	1
BLOOD_Leukemia	GTSF1L →	+0.613	+3.442	<.001	.005	3	1
BLOOD_Leukemia	SAA4 →	+0.024	+3.076	.007	.002	3	1
BLOOD_Leukemia	SPATA19 →	+0.011	+3.984	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

C9orf57 by FAM91A1 expression — BLOOD_Leukemia

Explore this box plot interactively →