Across TCGA pan-cancer cohorts, FAM90A2P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of FAM90A2P’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where FAM90A2P RNA is repressed in tumor relative to normal tissue. In most cancer types FAM90A2P is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.
BRCA, KICH, and CHOL are the cancer types where FAM90A2P tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM90A2P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.