FAM8A1

Across TCGA patient cohorts, FAM8A1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,043 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM8A1-associated genes across cancer lineages are SYTL1, MARCO, and G0S2. Each is linked with FAM8A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM8A1-to-partner and partner-to-FAM8A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM8A1 versus SYTL1 in UCEC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM8A1→partner) and Y-score (partner→FAM8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SYTL1 →	-1.397	-0.391	<.001	<.001	3	4
GBM	MARCO →	-2.083	-0.353	<.001	<.001	3	4
GBM	G0S2 →	-1.396	-0.273	.001	.005	3	3
HNSC	TBCEL →	+0.668	+0.526	<.001	<.001	3	3
GBM	ZNF606 →	+0.471	+0.291	.001	<.001	3	3
LSCC	CCDC149 →	+0.397	+0.219	.003	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,043 associations by consensus.

FAM8A1 vs SYTL1 — UCEC

Explore this scatter interactively →