FAM8A1

Across TCGA cell cohorts, FAM8A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,230 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM8A1-associated GO terms across cancer lineages are ERAD pathway, Golgi vesicle transport, and Regulation of pigment cell differentiation. Each is linked with FAM8A1 in more than 11 cancer types. Because this analysis shows association rather than direction, both FAM8A1-to-partner and partner-to-FAM8A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERAD pathway grouped by FAM8A1-low versus FAM8A1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM8A1→partner) and Y-score (partner→FAM8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ERAD pathway →	+0.073	+0.718	<.001	.001	3	12
OVARY	Golgi vesicle transport →	+0.055	+0.997	<.001	<.001	3	11
PANCREAS	Regulation of pigment cell differentiation →	+0.201	+0.503	.001	.001	3	10
PANCREAS	Positive regulation of pigment cell differentiation →	+0.201	+0.503	.001	.001	3	10
STOMACH	Endosomal lumen acidification →	+0.150	+1.125	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Copper ion export →	-0.190	-1.123	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,230 associations by consensus.

ERAD pathway by FAM8A1 expression — CNS

Explore this box plot interactively →