FAM89B

Across TCGA patient cohorts, FAM89B protein abundance is significantly associated with the RNA expression of many other genes, with 7,671 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM89B-associated genes across cancer lineages are FEZ1, COX7A1, and VTI1B. Each is linked with FAM89B in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM89B-to-partner and partner-to-FAM89B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM89B versus FEZ1 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM89B→partner) and Y-score (partner→FAM89B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FEZ1 →	+0.564	+0.231	<.001	.004	3	4
UCEC	COX7A1 →	+1.004	+0.416	<.001	<.001	3	4
GBM	VTI1B →	+0.375	+0.510	<.001	<.001	3	3
CCRCC	CINP →	+0.472	+0.524	<.001	<.001	3	3
GBM	LAMP5 →	+0.993	+0.320	<.001	<.001	3	3
GBM	FXYD6 →	+0.905	+0.308	.002	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,671 associations by consensus.

FAM89B vs FEZ1 — BRCA

Explore this scatter interactively →