FAM89B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM89B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,734 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM89B-associated GO terms across cancer lineages are Positive regulation of stem cell population maintenance, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of stem cell population maintenance. Each is linked with FAM89B in more than 10 cancer types. Because this analysis shows association rather than direction, both FAM89B-to-partner and partner-to-FAM89B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stem cell population maintenance grouped by FAM89B-low versus FAM89B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM89B→partner) and Y-score (partner→FAM89B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCPositive regulation of stem cell population maintenance →+0.084+1.006<.001<.001311
SOFT_TISSUENegative regulation of syncytium formation by plasma membrane fusion →+0.062+0.507<.001.001310
LUNG_SCLCRegulation of stem cell population maintenance →+0.075+1.066<.001<.00139
STOMACHRegulation of G1/S transition of mitotic cell cycle →+0.058+0.717.005.00239
LIVERDephosphorylation →+0.062+0.744<.001.00439
LARGE_INTESTINENegative regulation of myoblast fusion →+0.056+0.610.004.004210
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,734 associations by consensus.

Positive regulation of stem cell population maintenance by FAM89B expression — LUNG_SCLC

Box plot of Positive regulation of stem cell population maintenance in FAM89B-low vs FAM89B-high samples in LUNG_SCLC.

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Exploration