FAM89B

Across TCGA cell cohorts, FAM89B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FAM89B-associated genes across cancer lineages are UBQLN3, OR52L1, and OR8K3. Each is linked with FAM89B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM89B-to-partner and partner-to-FAM89B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBQLN3 grouped by FAM89B-low versus FAM89B-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM89B→partner) and Y-score (partner→FAM89B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	UBQLN3 →	+0.021	+4.672	<.001	.002	3	1
BREAST	OR52L1 →	+0.021	+4.672	<.001	.002	3	1
BREAST	OR8K3 →	+0.082	+4.781	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

UBQLN3 by FAM89B expression — BREAST

Explore this box plot interactively →