FAM86LP

Across TCGA pan-cancer cohorts, FAM86LP RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FAM86LP data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FAM86LP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM86LP expression acts as an unfavorable survival marker, although some lineages such as BLCA and SARC show a favorable association.

KIRC, THCA, and ACC are the cancer types where FAM86LP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.520	0.682	<.001	38	view →
THCA	OS	Median	All	0.816	0.978	.026	28	view →
ACC	OS	Tertile	IV	0.283	0.598	.013	27	view →
PRAD	DFS	Quartile	All	0.896	0.948	.010	22	view →
ESCA	DFS	Median	All	0.447	0.926	.004	20	view →
UCEC	OS	Quartile	All	0.886	0.936	.004	18	view →
THYM	OS	Tertile	II,III,IV	0.606	1.000	.005	14	view →
BLCA	DFS	Median	IV	0.327	0.115	.003	11	view →
SARC	OS	Tertile	All	0.900	0.654	.001	9	view →
KIRP	OS	Median	II,III,IV	0.840	0.613	.008	8	view →
LIHC	DFS	Tertile	III,IV	0.396	0.224	.031	8	view →
DLBC	OS	Tertile	II,III,IV	0.640	1.000	.037	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FAM86LP–KIRC (DFS)

Open the KIRC breakdown →