FAM86GP

Across TCGA pan-cancer cohorts, FAM86GP RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of FAM86GP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FAM86GP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM86GP is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KIRC, LIHC, and KICH are the cancer types where FAM86GP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM86GP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.864	<.001	12	view →
LIHC	Female	II,III,IV	+0.352	<.001	8	view →
KICH	Male	All	−0.668	<.001	7	view →
UCEC	All	All	−0.692	<.001	6	view →
BRCA	All	III,IV	−0.578	<.001	6	view →
COAD	All	All	+0.299	.002	5	view →
LUAD	All	All	+0.291	.002	5	view →
STAD	All	II,III,IV	+0.439	.011	4	view →
THCA	All	II,III,IV	−0.224	.009	4	view →
CHOL	All	II,III,IV	+1.060	.008	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

FAM86GP–KIRC

Open the KIRC breakdown →