FAM86B2

Across TCGA patient cohorts, FAM86B2 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM86B2-associated genes across cancer lineages are IGKV1OR-2, RNU4-89P, and NPB. Each is linked with FAM86B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86B2-to-partner and partner-to-FAM86B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGKV1OR-2 grouped by FAM86B2-low versus FAM86B2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86B2→partner) and Y-score (partner→FAM86B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV1OR-2 →	+0.298	+3.130	<.001	.003	3	1
UCEC	RNU4-89P →	+0.622	+3.698	.007	.003	3	1
UCEC	NPB →	+0.108	+4.082	<.001	.001	3	1
UCEC	MIR103A1 →	+0.257	+4.885	<.001	.002	3	1
UCEC	RNU6ATAC2P →	+0.270	+3.344	.005	.007	3	1
UCEC	TRBV11-1 →	+0.563	+3.909	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

IGKV1OR-2 by FAM86B2 expression — UCEC

Explore this box plot interactively →