FAM86B2

Across TCGA cell cohorts, FAM86B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,806 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM86B2-associated GO terms across cancer lineages are GMP biosynthetic process, Transcription by RNA polymerase I, and Acylglycerol acyl-chain remodeling. Each is linked with FAM86B2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM86B2-to-partner and partner-to-FAM86B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP biosynthetic process grouped by FAM86B2-low versus FAM86B2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86B2→partner) and Y-score (partner→FAM86B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GMP biosynthetic process →	+0.090	+0.556	<.001	<.001	3	6
SKIN	Transcription by RNA polymerase I →	+0.069	+0.508	.001	.004	3	6
OVARY	Acylglycerol acyl-chain remodeling →	-0.178	-0.460	.002	.006	3	5
LUNG_NSCLC_LUAD	rRNA metabolic process →	+0.048	+0.582	<.001	<.001	3	5
LUNG_NSCLC_LUAD	Positive regulation of telomerase RNA localization to Cajal body →	+0.055	+0.726	.003	<.001	3	5
BLOOD_Leukemia	rRNA processing →	+0.053	+0.412	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,806 associations by consensus.

GMP biosynthetic process by FAM86B2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →