Across TCGA pan-cancer cohorts, FAM86B1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FAM86B1 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher FAM86B1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM86B1 expression acts as an unfavorable survival marker.

KICH are the cancer types where FAM86B1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.102	0.848	.004	13	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: FAM86B1 tumor-vs-normal RNA expression · all FAM86B1 data types