Across TCGA patient cohorts, FAM86B1 mutation is significantly associated with the RNA expression of many other genes, with 174 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM86B1-associated genes across cancer lineages are IL9, RPL7L1P4, and MFSD4BP1. Each is linked with FAM86B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86B1-to-partner and partner-to-FAM86B1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86B1→partner) and Y-score (partner→FAM86B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	IL9 →	+0.468	+5.037	<.001	.009	3	2
UCEC	RPL7L1P4 →	+0.304	+2.670	<.001	.009	3	2
UCEC	MFSD4BP1 →	+0.181	+2.528	<.001	.006	3	2
UCEC	RNA5SP420 →	+1.083	+2.967	<.001	.002	3	2
BRCA	MIR6074 →	+0.327	+7.731	<.001	.009	3	1
SKCM	RNU6-319P →	+0.669	+5.362	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 174 associations by consensus.

Exploration

FAM86B1 survival (RNA) · tumor vs normal (RNA) · all FAM86B1 data types