FAM85B

Across TCGA pan-cancer cohorts, FAM85B RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FAM85B data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FAM85B RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated FAM85B expression acts as an unfavorable survival marker, although some lineages such as KIRC and UVM show a favorable association.

KIRC, UVM, and KIRP are the cancer types where FAM85B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.742	0.508	<.001	46	view →
UVM	DFS	Tertile	II,III,IV	0.813	0.381	.002	41	view →
KIRP	DFS	Median	IV	0.039	0.623	.001	29	view →
HNSC	DFS	Median	IV	0.630	0.467	.001	27	view →
COAD	OS	Quartile	II,III,IV	0.927	0.551	<.001	25	view →
PAAD	DFS	Median	All	0.354	0.560	.005	20	view →
STAD	DFS	Median	III,IV	0.568	0.253	.012	19	view →
ACC	OS	Tertile	IV	0.363	0.750	.022	16	view →
DLBC	DFS	Quartile	II,III,IV	1.000	0.454	.014	11	view →
BLCA	OS	Tertile	II,III,IV	0.770	0.667	.023	7	view →
MESO	OS	Tertile	All	0.734	0.292	.033	6	view →
THYM	DFS	Median	II,III,IV	0.704	0.988	.003	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FAM85B–KIRC (DFS)

Open the KIRC breakdown →