Across TCGA pan-cancer cohorts, FAM83G mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FAM83G data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FAM83G mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FAM83G expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, HNSC, and PDAC are the cancer types where FAM83G mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	1.000	0.424	.003	32	view →
HNSC	DFS	Tertile	All	0.787	0.564	.018	9	view →
PDAC	DFS	Median	All	0.382	0.215	.020	6	view →
LUAD	OS	Quartile	II,III,IV	0.326	0.866	.010	5	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.826	.027	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: FAM83G tumor-vs-normal RNA expression · all FAM83G data types