FAM83D

Across TCGA patient cohorts, FAM83D protein abundance is significantly associated with the RNA expression of many other genes, with 10,269 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM83D-associated genes across cancer lineages are ANLN, DEPDC1, and GINS1. Each is linked with FAM83D in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM83D-to-partner and partner-to-FAM83D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM83D versus ANLN in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83D→partner) and Y-score (partner→FAM83D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANLN →	+1.042	+0.498	<.001	<.001	3	5
UCEC	DEPDC1 →	+2.052	+0.922	<.001	.002	3	5
UCEC	GINS1 →	+1.722	+0.868	<.001	.005	3	4
OV	FOXM1 →	+1.338	+0.545	<.001	.003	3	4
UCEC	TTK →	+2.047	+0.938	<.001	.002	3	4
BRCA	CDC20 →	+1.642	+0.938	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,269 associations by consensus.

FAM83D vs ANLN — BRCA

Explore this scatter interactively →