FAM83D

Across TCGA cell cohorts, FAM83D mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM83D-associated genes across cancer lineages are OR11H2, TNP1, and KRT6C. Each is linked with FAM83D in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM83D-to-partner and partner-to-FAM83D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H2 grouped by FAM83D-low versus FAM83D-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83D→partner) and Y-score (partner→FAM83D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR11H2 →	+0.040	+4.927	<.001	.001	3	2
SOFT_TISSUE	TNP1 →	+1.481	+5.369	<.001	.004	3	1
SOFT_TISSUE	KRT6C →	+0.013	+4.930	<.001	.008	3	1
SOFT_TISSUE	RLN3 →	+0.041	+5.369	<.001	.004	3	1
LUNG_NSCLC_LUAD	C1orf232 →	+0.054	+4.887	<.001	.009	3	1
STOMACH	CCL7 →	+0.167	+3.432	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

OR11H2 by FAM83D expression — BLOOD_Lymphoma

Explore this box plot interactively →