FAM81A

Across TCGA patient cohorts, FAM81A protein abundance is significantly associated with the RNA expression of many other genes, with 1,659 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM81A-associated genes across cancer lineages are PRODH, RASL10A, and NEFH. Each is linked with FAM81A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM81A-to-partner and partner-to-FAM81A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM81A versus PRODH in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM81A→partner) and Y-score (partner→FAM81A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.802	+0.333	.002	<.001	3	1
GBM	RASL10A →	+0.790	+0.380	<.001	<.001	3	1
GBM	NEFH →	+0.982	+0.355	<.001	<.001	3	1
GBM	RASD2 →	+0.478	+0.397	.002	<.001	3	1
GBM	PNPLA5 →	+0.206	+0.353	<.001	<.001	3	1
GBM	CACNA1I →	+0.634	+0.506	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,659 associations by consensus.

FAM81A vs PRODH — GBM

Explore this scatter interactively →