FAM81A

Across TCGA cell cohorts, FAM81A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,422 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FAM81A-associated GO terms across cancer lineages are Mitotic sister chromatid cohesion, Positive regulation of nuclear cell cycle DNA replication, and Positive regulation of DNA-directed DNA polymerase activity. Each is linked with FAM81A in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM81A-to-partner and partner-to-FAM81A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic sister chromatid cohesion grouped by FAM81A-low versus FAM81A-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM81A→partner) and Y-score (partner→FAM81A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Mitotic sister chromatid cohesion →	+0.113	+2.098	<.001	<.001	3	8
BLOOD_Lymphoma	Positive regulation of nuclear cell cycle DNA replication →	+0.090	+1.911	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA-directed DNA polymerase activity →	+0.144	+1.097	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation involved in DNA replication →	+0.169	+1.238	.001	<.001	3	8
STOMACH	Regulation of neuron apoptotic process →	-0.062	-1.640	<.001	.002	3	8
BLOOD_Lymphoma	Regulation of animal organ formation →	-0.651	-1.970	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,422 associations by consensus.

Mitotic sister chromatid cohesion by FAM81A expression — SOFT_TISSUE

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