Across TCGA pan-cancer cohorts, FAM72A Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FAM72A data layer compared with 29 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher FAM72A Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM72A expression acts as an unfavorable survival marker.

CESC are the cancer types where FAM72A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	All	0.193	0.740	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: FAM72A tumor-vs-normal RNA expression · all FAM72A data types