FAM71F1

Across TCGA pan-cancer cohorts, FAM71F1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FAM71F1 data layer compared with 19 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FAM71F1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM71F1 expression acts as an unfavorable survival marker.

HNSC, MESO, and LUAD are the cancer types where FAM71F1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.156	0.710	.002	24	view →
MESO	DFS	Median	III,IV	0.078	0.376	.012	9	view →
LUAD	OS	Median	II,III,IV	0.237	0.709	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FAM71F1–HNSC (OS)

Open the HNSC breakdown →