FAM71F1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FAM71F1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FAM71F1 data layer compared with 19 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher FAM71F1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FAM71F1 expression acts as an unfavorable survival marker.

PDAC, LUAD, and LSCC are the cancer types where FAM71F1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACOSTertileAll0.3970.626.00425view →
LUADOSTertileAll0.3530.795.00413view →
LSCCDFSTertileAll0.6270.898.0223view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FAM71F1–PDAC (OS)

Kaplan–Meier survival curve for FAM71F1 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration