FAM71F1

Across TCGA patient cohorts, FAM71F1 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM71F1-associated genes across cancer lineages are IGFBP2, JNK_pT183_Y185, and JNK2. Each is linked with FAM71F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM71F1-to-partner and partner-to-FAM71F1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGFBP2 grouped by FAM71F1-low versus FAM71F1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71F1→partner) and Y-score (partner→FAM71F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGFBP2 →	-0.553	-1.700	.045	.044	3	1
UCEC	JNK_pT183_Y185 →	-0.184	-3.459	.010	.005	3	1
UCEC	JNK2 →	+0.200	+1.700	.017	.044	3	1
UCEC	PCNA →	+0.187	+1.700	.042	.044	3	1
UCEC	ATM →	-0.555	-2.222	.003	.011	3	1
UCEC	Caspase-8 →	-0.228	-3.432	.032	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

IGFBP2 by FAM71F1 expression — UCEC

Explore this box plot interactively →