FAM71F1

Across TCGA cell cohorts, FAM71F1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM71F1-associated genes across cancer lineages are CHRNB3, SPATA31D1, and CFHR2. Each is linked with FAM71F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM71F1-to-partner and partner-to-FAM71F1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHRNB3 grouped by FAM71F1-low versus FAM71F1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71F1→partner) and Y-score (partner→FAM71F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CHRNB3 →	+0.011	+4.467	<.001	.004	3	1
LUNG_NSCLC_LUAD	SPATA31D1 →	+0.006	+5.228	<.001	.005	3	1
LARGE_INTESTINE	CFHR2 →	+0.032	+3.700	<.001	.009	3	1
LARGE_INTESTINE	CLEC18C →	+0.159	+3.333	.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CHRNB3 by FAM71F1 expression — SKIN

Explore this box plot interactively →