FAM71E1

Across TCGA patient cohorts, FAM71E1 mutation is significantly associated with the RNA expression of many other genes, with 575 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM71E1-associated genes across cancer lineages are RPL14P6, NIPA2P3, and CYCSP42. Each is linked with FAM71E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM71E1-to-partner and partner-to-FAM71E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL14P6 grouped by FAM71E1-low versus FAM71E1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71E1→partner) and Y-score (partner→FAM71E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL14P6 →	+0.205	+3.798	.005	.009	3	2
BLCA	NIPA2P3 →	+0.029	+7.640	<.001	.009	3	1
PRAD	CYCSP42 →	+0.089	+7.939	<.001	.008	3	1
UCEC	RNA5SP414 →	+0.527	+2.769	.002	.002	3	1
UCEC	MRPL57P3 →	+0.474	+2.761	.002	.001	3	1
UCEC	UHRF1 →	+1.373	+3.470	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 575 associations by consensus.

RPL14P6 by FAM71E1 expression — COAD

Explore this box plot interactively →