FAM71E1

Across TCGA patient cohorts, FAM71E1 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM71E1-associated genes across cancer lineages are MIG-6, p27_pT157, and ASNS. Each is linked with FAM71E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM71E1-to-partner and partner-to-FAM71E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIG-6 grouped by FAM71E1-low versus FAM71E1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71E1→partner) and Y-score (partner→FAM71E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIG-6 →	-0.111	-2.990	.042	.036	3	1
UCEC	p27_pT157 →	-0.070	-2.960	.026	.036	3	1
UCEC	ASNS →	+0.609	+3.169	.002	.019	3	1
UCEC	Fibronectin →	-0.404	-3.169	.025	.020	2	1
UCEC	ACC_pS79 →	+0.470	+3.169	.013	.020	2	1
UCEC	Heregulin →	-0.203	-3.169	.002	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

MIG-6 by FAM71E1 expression — UCEC

Explore this box plot interactively →