FAM71B

Across TCGA patient cohorts, FAM71B mutation is significantly associated with the RNA expression of many other genes, with 2,316 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM71B-associated genes across cancer lineages are PSMD9, SNF8, and UFD1. Each is linked with FAM71B in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM71B-to-partner and partner-to-FAM71B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMD9 grouped by FAM71B-low versus FAM71B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71B→partner) and Y-score (partner→FAM71B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PSMD9 →	+0.192	+1.767	.008	<.001	3	4
UCEC	SNF8 →	+0.374	+2.151	<.001	<.001	3	4
UCEC	UFD1 →	+0.296	+1.609	.001	.005	3	4
LUAD	SIDT1 →	-0.829	-2.274	<.001	.006	3	4
LIHC	RN7SL474P →	+0.110	+6.169	<.001	<.001	3	3
LGG	RNU6-603P →	+0.403	+6.245	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,316 associations by consensus.

PSMD9 by FAM71B expression — SKCM

Explore this box plot interactively →