Across TCGA patient cohorts, FAM66C RNA expression is significantly associated with the protein abundance of many other proteins, with 19,878 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM66C-associated proteins across cancer lineages are HDGFL3, ABI2, and TCEAL4. Each is linked with FAM66C in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM66C-to-partner and partner-to-FAM66C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM66C→partner) and Y-score (partner→FAM66C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HDGFL3 →	+0.818	+0.566	<.001	<.001	3	8
HNSC	ABI2 →	+0.407	+0.987	<.001	<.001	3	7
BRCA	TCEAL4 →	+0.587	+0.322	<.001	.002	3	7
UCEC	PTMS →	+0.489	+0.883	<.001	<.001	3	6
HNSC	VCAN →	+0.789	+0.504	<.001	<.001	3	6
HNSC	VEZF1 →	+0.433	+0.773	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,878 associations by consensus.

Exploration

FAM66C survival (RNA) · tumor vs normal (RNA) · all FAM66C data types