Across TCGA patient cohorts, FAM66A RNA expression is significantly associated with the go_rna of many other GO terms, with 7,109 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible FAM66A-associated GO terms across cancer lineages are Histone mRNA metabolic process, Rac protein signal transduction, and Negative regulation of protein sumoylation. Each is linked with FAM66A in more than 28 cancer types. Because this analysis shows association rather than direction, both FAM66A-to-partner and partner-to-FAM66A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM66A→partner) and Y-score (partner→FAM66A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Histone mRNA metabolic process →	+0.048	+1.092	<.001	<.001	3	29
LAML	Rac protein signal transduction →	+0.048	+0.536	<.001	<.001	3	28
TGCT	Negative regulation of protein sumoylation →	+0.079	+0.976	<.001	<.001	3	28
LAML	Protein localization to chromosome, telomeric region →	+0.050	+0.489	<.001	<.001	2	29
THYM	Regulation of macroautophagy →	+0.045	+0.401	<.001	<.001	3	27
LAML	Obsolete histone methylation →	+0.072	+0.535	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,109 associations by consensus.

Exploration

FAM66A survival (RNA) · tumor vs normal (RNA) · all FAM66A data types