Across TCGA patient cohorts, FAM66A mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM66A-associated genes across cancer lineages are IGKV1OR-2, MIR6859-2, and GCNT1P1. Each is linked with FAM66A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM66A-to-partner and partner-to-FAM66A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM66A→partner) and Y-score (partner→FAM66A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV1OR-2 →	+0.296	+2.715	<.001	.006	3	1
UCEC	MIR6859-2 →	+0.485	+2.783	<.001	.008	3	1
SKCM	GCNT1P1 →	+0.083	+3.539	.002	.007	3	1
SKCM	MIR6508 →	+0.387	+3.300	<.001	.007	3	1
BLCA	RNU6-258P →	+0.328	+7.640	<.001	.009	3	1
LUAD	DEFB103A →	+0.059	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

Exploration

FAM66A survival (RNA) · tumor vs normal (RNA) · all FAM66A data types