FAM66A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM66A mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM66A-associated genes across cancer lineages are Platelets, NKT, and Basophils. Each is linked with FAM66A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM66A-to-partner and partner-to-FAM66A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM66A→partner) and Y-score (partner→FAM66A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMPlatelets →+0.021+2.769.006.00832
UCECNKT →-0.133-2.975.031.03631
UCECBasophils →+0.237+3.000.015.03721
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration