Across TCGA patient cohorts, FAM53B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,491 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM53B-associated proteins across cancer lineages are PHRF1_S814, FAM53B_S167, and SEC24D. Each is linked with FAM53B in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM53B-to-partner and partner-to-FAM53B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM53B→partner) and Y-score (partner→FAM53B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PHRF1_S814 →	-0.891	-0.733	<.001	<.001	3	6
OV	FAM53B_S167 →	+0.682	+0.597	.001	.002	3	5
LSCC	SEC24D →	-0.404	-0.534	<.001	<.001	3	4
HNSC	GTF2I →	+0.406	+0.636	<.001	.002	3	4
CCRCC	HDLBP_S944 →	-0.725	-0.391	.001	<.001	3	4
PDAC	MADD_S1239 →	+0.750	+0.371	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,491 associations by consensus.

Exploration

FAM53B survival (RNA) · tumor vs normal (RNA) · all FAM53B data types