Across TCGA patient cohorts, FAM53B protein abundance is significantly associated with the RNA expression of many other genes, with 3,543 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FAM53B-associated genes across cancer lineages are FAM53B-AS1, PIK3IP1, and VAMP4. Each is linked with FAM53B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM53B-to-partner and partner-to-FAM53B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM53B→partner) and Y-score (partner→FAM53B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FAM53B-AS1 →	+0.819	+0.440	<.001	<.001	3	3
GBM	PIK3IP1 →	+0.813	+0.315	.001	.008	3	2
UCEC	VAMP4 →	-0.412	-0.214	.005	.004	3	2
LUAD	COQ6 →	-0.366	-0.446	<.001	<.001	3	2
HNSC	HCST →	+0.931	+0.200	.001	.005	3	2
LUAD	PTGR2 →	-0.520	-0.345	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,543 associations by consensus.

Exploration

FAM53B survival (RNA) · tumor vs normal (RNA) · all FAM53B data types