Across TCGA cell cohorts, FAM53B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,909 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FAM53B-associated GO terms across cancer lineages are Copper ion export, Viral translational termination-reinitiation, and Regulation of brown fat cell differentiation. Each is linked with FAM53B in more than 13 cancer types. Because this analysis shows association rather than direction, both FAM53B-to-partner and partner-to-FAM53B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM53B→partner) and Y-score (partner→FAM53B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Copper ion export →	-0.180	-0.881	<.001	.001	2	14
LARGE_INTESTINE	Viral translational termination-reinitiation →	+0.083	+0.898	<.001	<.001	3	12
STOMACH	Regulation of brown fat cell differentiation →	+0.123	+1.204	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of myoblast differentiation →	+0.120	+0.906	<.001	<.001	3	12
BREAST	Urokinase plasminogen activator signaling pathway →	-1.115	-0.833	.001	<.001	3	10
LUNG_NSCLC_LUSC	Symbiont-mediated disruption of host cell PML body →	+0.101	+0.707	.001	.008	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,909 associations by consensus.

Exploration

FAM53B survival (RNA) · tumor vs normal (RNA) · all FAM53B data types