FAM43B

Across TCGA patient cohorts, FAM43B RNA expression is significantly associated with the protein abundance of many other proteins, with 9,783 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM43B-associated proteins across cancer lineages are MRPS5, PCOLCE, and CLEC11A. Each is linked with FAM43B in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM43B-to-partner and partner-to-FAM43B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPS5 grouped by FAM43B-low versus FAM43B-high in BRCA.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM43B→partner) and Y-score (partner→FAM43B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MRPS5 →	-0.309	-0.330	<.001	<.001	3	6
BRCA	PCOLCE →	+0.820	+0.408	<.001	<.001	3	6
BRCA	CLEC11A →	+0.725	+0.285	<.001	.005	3	6
HNSC	FHL3 →	+0.539	+0.217	<.001	.004	3	6
UCEC	NID2 →	+0.583	+0.530	.005	.004	3	6
COAD	RSU1 →	+0.345	+0.119	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,783 associations by consensus.

MRPS5 by FAM43B expression — BRCA

Explore this box plot interactively →